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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8a23011329dbe75fc3185bd34e5cc34f1e67b8c3757396a1c363031d5b8969' 
  AND token = 'KXUH+L9nDT0lCLFPmaZ3QBRag2pLm79KfkFPZwL7y4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}