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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c906b79a3aa39266295b5af6b2a0b2bc6313d9d586ad22664c35b50f82843ab7' 
  AND token = 'gyhsRrj9pVodHqcU80zcG68nYAtWBZmIE85+SulsRnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}