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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b42e511a45acb83e478e2505a78b0b6c32aec7e9a9eb7780573f39ef4e619de' 
  AND token = 'O3dJYk7YjH8x/PSnXM/LSYToYWY4anI7CXgA6C8YPAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}