SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c558180560db42aa099534c53e6030feec69774f2609afbc37fb99d1ebeb2837' 
  AND token = 'G6Q3epPzrmpVgXiSaNjGt+rThty/XKno2dI0vaHzb1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}