SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2de3190116863d728289fa25add32a855ea9b06042915e1230d23f74a0aecfd' 
  AND token = 'YCxwXQK8Owz7XrZ6QbhYgtpozfmR6Wv6fNXa2490ZuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}