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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8281be67066c9d1d1b59fa5536db7a372b67cca04d4bab89aa053193e3556dc3' 
  AND token = '8uN5E2MSG5EhTzv9AN5Me6ZyYVmPm4BUV2KbUSu1Kjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}