SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01f5fd94c831a2803657f687324b3b081e600e2633c389691f7504918ba34af2' 
  AND token = 'xTI9K2RZInHCjo1E6TkDtzuKMCz0Y2zJ1yo416/nV0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}