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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05dc2f776af42b012a58ce71c856617175312cce209d4658392520b6603adb0' 
  AND token = 'd5cyADlaY1LeRAuzVAKMJXzVIjGE4D9v1tvc0G7Xurw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}