SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aebc75de25f1bd9446665d303c76263a430b8b3042c917b1930d384a29ae2b3' 
  AND token = 'DPEmNMkWWQ8AKIbSx7ShdWdyc0YNavmaUYpjvkiCU5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}