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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddc1670b3a97d85e89fe235385534e98c90d8864cd7930fe9493a9c9537bdb49' 
  AND token = 'r3oPMLHTPxg6P0f3n3TvQpdO0oxcdB9DX0RCBoq9BrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}