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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1512348a50b06e71a915c53c67e361c8caa3d6578103d3b3347cc3a31f131a8f' 
  AND token = 'kDe+/ayTelnxMd4quSVAqUY+X+rT11Jd28KR5dk0tfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}