SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce72e1696a7c3093292dfd19d4db22e9f28842424b790cb46822cf03877d7841' 
  AND token = 'IMTAqkUfbod4OZpHF7hTHVQl+iPale6YF/jWxqWBxBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}