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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9eac29fbd74dad32faf8c46858bcdecdf5f50d4ede28bf79c9541cc05d2e639' 
  AND token = 'IXfMqlH4gNku8qBX5Yb+3C0ChrbANd+u/UsfDj7V4xM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}