SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53b68feb786ab837eab61c47fdf9f51a9ac8b8cdb81455e421196281e4aae2d' 
  AND token = 'RSccu+WfA6A5k4dZmfxmcnz1KW8ueTcb5ptdR2rhsnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}