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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2142de68507f5357fbdc9536f5b7ebf85af7ba247eac67eddf7a4c65ac30b7f7' 
  AND token = 'aBPDjcCtA0B7+e2aFCJ1sqZSF4FAx28JDIsLuiOKQvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}