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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95605f4bdc486991c9fa4b85e1f3f1f030fdd06f97d9f4e7a0cf84901a4f8748' 
  AND token = 'dtrTIE6cYHwTkqevgFNDEzbggYTQT/qRCcfcpF1nsgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}