SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '785c1c9941515cce32da51971b6a1fae76522e903b122d168dc0443b9b28222a' 
  AND token = 'UaRS+Ch5egnYqz9uOAsgAt/J0w76wijPncgi0BZu7i8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}