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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f39d5de95d3aff87f35420fd47dd9789651754a5941e1d4c993cc5cea5731d' 
  AND token = 'UhUB+MMqR8sIALE85M4Yjzssz1rjs9fFg1Pn3a/lqIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}