SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '000f4c85968ca527ad211d0e02fd5332e8d35c9aef2355c24044e9e535c6fb23' 
  AND token = 'nWG1gtFaOvjlEzpTRM+LkILIYwdA1VTftAmR04axlkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}