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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8d56dc4552bb0b810ef4be70b49b12fca1e3296d94a70358fa2dba1ed90591' 
  AND token = 'BShSfBMJJ/4Y+xp5k/d5QBXEIMA1BG+HO5ewkNF7njA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}