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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5fc2ad1a708acb574e580463245ee299e7d4c8bbc068ad5e33d3e53fdcd3454' 
  AND token = 'vUJiKctqazCIYwg8SS8aDsmvIMQ05jWriNRNXxM/ACI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}