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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '497083951f25214cc2b1cbc69f901dcaee6eee1b1cd2bd4bb670a93d14370182' 
  AND token = 'RErdVUbjje3AiJ+0yYdIvOEqgHEnZ4lJU0wKucVxB6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}