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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a0fce295333f27eacf139bbde5da2c9cbf44e47aebd05ecf5f33dc21ca8496c' 
  AND token = 'yPo4avhBnUW8M72AE6as6Q8YLWIlGSHbNxt2+0NdtkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}