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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8431c9c23ecba6d7c36019b938be68e995369eef72d65d3fe90447feda80dc2e' 
  AND token = 'HDReQ3MlAmfsM0CTS4NaoRny7yLR77P0TRkGim8xZvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}