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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '673ccf45d4eee8d052dc8ef155d679b122c5ee50f04162dfff18ce4ff536854f' 
  AND token = 'iR6egyY1cQ/1y/aX3dXn4F3nTlwc+ASS9gqp+2muvZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}