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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '487f8897d767899c71867a1cd5ee885ec71712f84455d527a745c3f55d85afca' 
  AND token = 'j6jj+RrYe9i/diOaRY/e9jIzowIWYARsB576HPLbkBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}