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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78817c06d22f9337358d48dc96ff6925c9c4a0a7e88d5864bd6c1cd0d8833317' 
  AND token = 'QlTAwP4TuNIgo0XBBzhxu4LCJpsBX1WQYASygQx0wxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}