SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09f7d2fdfd57582b1f542da3850f8119e0fd0593fc3b261c93fc49faa07c0de2' 
  AND token = 'OAGZcK0Oni/F+eY0DLvSmZzxYERxV2wLPPK0F5kRZVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}