SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8c7161c9b748a8ff47f564ce19e68e9eb69dc291026c9b8a7438f20d5f597c2' 
  AND token = 'jT8j/HuGvfoQeo4uLnaYGoppnC2yenBmGfmWQ8CFZSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}