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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '264ed2312c6d854c0a315accdde4887233e014dc878b66b0ce55a8341a9e8faf' 
  AND token = '2xrwv5eTIjv61dEzE1QsacOqtsRP/AFEMiJi2mSp0tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}