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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70f83a1b4ea741acc201efd0c1f579a4bf45e662d3a6e30c4b591febf5d1db72' 
  AND token = 'dXWxwMm+OT+D44IqJ3DI5SC658ljOA01HIh7AS8hhZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}