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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1e619f01769dfce7ac4a21105bc37aea28f2d2aa01c97ec6384e2dab2c3762' 
  AND token = 'XZzSYqXRkqOZdOQG4da43NnldBR78UGy9lEAWkfIl4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}