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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb8b4780cd9c50ff75ecb594ce9d36f83a44bff34eced50a84d95d836c22c65a' 
  AND token = 'bQUb9iruIKEt3q3+v960ZnleAA3oYVM0NyDauJXugIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}