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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57ac50efb6b80c25b67ddf19a8faa3414c9af845529e5d0e6d7062ecacffa945' 
  AND token = 'zXKU8X/DSYsQ1lP/GbcPHuNc2lL8wlj8CbUFs5R6Wcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}