SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c918e6ff9c09d9c3f35dde2b2b7ebbdd47d55790803f5802f4d54d258ac3aa04' 
  AND token = 'Ib4cKHM0PQHyXDtnfbXhdBliAy0g5insQtfUQkLTatc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}