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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f15def0793407eeb86e18f0447b0c701f226aa0bb7a08c5b4c91bf0f1e75a295' 
  AND token = 'M/1V2bG7IWDZIItkuOm1QYCln5fFGLbjG/QWQLaIGQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}