SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39f1df05f660067465a59b99e126ac76e279dc5f0768fb60a9ed76fbd732ffa0' 
  AND token = 'Mb5rEuU1RInGiLct1+ekNm4wddMlenPLIlxHH15tRVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}