SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44f8bfcf806d88a5307abedcb7650800122452e69093256de0b7437079e9ae3a' 
  AND token = '3UH1+b0EMAVq4Lf9bPbB1Yxpl7HnVv9BESto+W6rfMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}