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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f2c38dc4e3a213d689afeb206adff70a80c248f685f809bcf631e0364b3c36b' 
  AND token = '6Ttx2fnMPuJ+WnLyagQReYjBfquf08x5BmjAa1XAeMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}