SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46da4ce72040d14e6a12885220bd2c198f1ad5a5c50123ae42ba20b20a760602' 
  AND token = 'Asp43OnlqYF70lu4GXxP9kexNJP87yePjeZV0pkrjF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}