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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3c1d6b243fbbdf0bf5b64cf838b6e98d6f6408dd5690c7e3ede8bf3b29606fb' 
  AND token = 'QT3BJzWs20BuB3BrrwOEzb0587wmx0oOnzxqhnqDU5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}