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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1a5c0cf48b5b67374f807a272c9b08424cbf1a72fc71cd76ffab4f05250c60f' 
  AND token = 'wKn43Mx6c/jZ6IB4yLeMETj30+7rTLaYmFOG9saLd1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}