SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e4263cece62256f579c3c53ee969c1eed8138aa23cc8fdc2714de0e2b98c94' 
  AND token = '6SrRwjpaaKWKAxUC/uItkmshgbFPG2VuFKa5MQcxmHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}