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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a60ff6d41f3259b37f07462b070af39c4022178ede894aa768af7c8fa2aaaed9' 
  AND token = 'I8S/oejpaXt+gNgrEuYjHw2N21O3aT6EJnQcoPabBk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}