SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db0582f4494642a76613d82492ca275ed603edf350a50dfd0b59f3ca81a89569' 
  AND token = 'MfVLTjsI0h/+UlNDNM1PHJt4e0RMBOpOw4UgPxaNNDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}