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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d100f0036f9214fd6c97e300ff2313f62c7c9a054cb772ff9f95911a3c77130' 
  AND token = '69M4RgGrplvFNYG86Q02MsZdnd76TKUgz2eJwPjdtNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}