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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3c505b9649557faea94cb2ade4056c5375faa478e3fde77bdfd5c106c453a55' 
  AND token = 'Vm+ItXcjXmy/8QkytN92hhDU6LEG9WfwfSF7Y6//63o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}