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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aec37daad18faf9cec55d21dfd9f105d7e0268f615eb5a64a3cf693ce572cb99' 
  AND token = 'M8mBZHzWWmoRA/EwjYrbLp74zezh9opzMR2Z+Q31Va0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}