SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295b811628cd44af33a8bbf33c522bea03900cdad7f3a81cf162ec0d0140001f' 
  AND token = 'NrSW3zHP1jBWvjQaSWVTZrMrnz2Uyq3AZKOY2fzuiyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}