SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d2d0164319c2cdc9b608d9f3fcb015d49735aa40bdb4d184ded0dbe20e47ad4' 
  AND token = 'RhETjynGkOxCcM49f+iNYMVEqajLfd3V+mB7ynk7a6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}